Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 539.7 BDBM50443290

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase type 3 (Rattus norvegicus)	BDBM50443290 (CHEMBL3088089) Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@]5(CC[C@]34C)CN(Cc3ccccc3)[C@@H](Cc3ccccc3)C(=O)O5)[C@@H]1CCC2=O |r| Show InChI InChI=1S/C36H45NO3/c1-34-19-20-36(22-27(34)13-14-28-29-15-16-32(38)35(29,2)18-17-30(28)34)24-37(23-26-11-7-4-8-12-26)31(33(39)40-36)21-25-9-5-3-6-10-25/h3-12,27-31H,13-24H2,1-2H3/t27-,28-,29-,30-,31-,34-,35-,36+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Laval University Curated by ChEMBL					Assay Description Inhibition of 17beta-HSD3 in rat testes microsomal fraction using [14C]-4-androstene-3,17-dione as substrate assessed as testosterone formation after...				Bioorg Med Chem Lett 23: 6360-2 (2013) Article DOI: 10.1016/j.bmcl.2013.09.072 BindingDB Entry DOI: 10.7270/Q2KP83M4
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