Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 394.4 BDBM50101552

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50101552 (3-[4-(4-Fluoro-phenoxy)-phenyl]-1-(2-hydroxy-1-met...) Show SMILES C[C@H]([C@@H](O)c1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C23H23FN2O3/c1-16(22(27)17-6-4-3-5-7-17)26(2)23(28)25-19-10-14-21(15-11-19)29-20-12-8-18(24)9-13-20/h3-16,22,27H,1-2H3,(H,25,28)/t16-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Neuropeptide Y2 Receptor.				J Med Chem 44: 2344-56 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J56
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50101552 (3-[4-(4-Fluoro-phenoxy)-phenyl]-1-(2-hydroxy-1-met...) Show SMILES C[C@H]([C@@H](O)c1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C23H23FN2O3/c1-16(22(27)17-6-4-3-5-7-17)26(2)23(28)25-19-10-14-21(15-11-19)29-20-12-8-18(24)9-13-20/h3-16,22,27H,1-2H3,(H,25,28)/t16-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Neuropeptide Y1 Receptor.				J Med Chem 44: 2344-56 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J56
					More data for this Ligand-Target Pair