Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 376.4 BDBM50101549

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50101549 (1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...) Show SMILES C[C@H]([C@@H](O)c1ccccc1)N(C)C(=O)Nc1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C23H24N2O3/c1-17(22(26)18-10-5-3-6-11-18)25(2)23(27)24-19-12-9-15-21(16-19)28-20-13-7-4-8-14-20/h3-17,22,26H,1-2H3,(H,24,27)/t17-,22-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Neuropeptide Y5 Receptor.				J Med Chem 44: 2344-56 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J56
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50101549 (1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...) Show SMILES C[C@H]([C@@H](O)c1ccccc1)N(C)C(=O)Nc1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C23H24N2O3/c1-17(22(26)18-10-5-3-6-11-18)25(2)23(27)24-19-12-9-15-21(16-19)28-20-13-7-4-8-14-20/h3-17,22,26H,1-2H3,(H,24,27)/t17-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Neuropeptide Y1 Receptor.				J Med Chem 44: 2344-56 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J56
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50101549 (1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...) Show SMILES C[C@H]([C@@H](O)c1ccccc1)N(C)C(=O)Nc1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C23H24N2O3/c1-17(22(26)18-10-5-3-6-11-18)25(2)23(27)24-19-12-9-15-21(16-19)28-20-13-7-4-8-14-20/h3-17,22,26H,1-2H3,(H,24,27)/t17-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Neuropeptide Y2 Receptor.				J Med Chem 44: 2344-56 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J56
					More data for this Ligand-Target Pair