Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50101536
(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)Show SMILES C[C@H]([C@H](O)c1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C23H24N2O3/c1-17(22(26)18-9-5-3-6-10-18)25(2)23(27)24-19-13-15-21(16-14-19)28-20-11-7-4-8-12-20/h3-17,22,26H,1-2H3,(H,24,27)/t17-,22+/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 477 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Tested in a cellular assay measuring forskolin-induced cyclic AMP accumulation in 293 cells transfected with the human NPY5 receptor |
J Med Chem 44: 2344-56 (2001)
BindingDB Entry DOI: 10.7270/Q2DV1J56 |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50101536
(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)Show SMILES C[C@H]([C@H](O)c1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C23H24N2O3/c1-17(22(26)18-9-5-3-6-10-18)25(2)23(27)24-19-13-15-21(16-14-19)28-20-11-7-4-8-12-20/h3-17,22,26H,1-2H3,(H,24,27)/t17-,22+/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Inhibitory activity tested against Human Neuropeptide Y5 Receptor. |
J Med Chem 44: 2344-56 (2001)
BindingDB Entry DOI: 10.7270/Q2DV1J56 |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50101536
(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)Show SMILES C[C@H]([C@H](O)c1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C23H24N2O3/c1-17(22(26)18-9-5-3-6-10-18)25(2)23(27)24-19-13-15-21(16-14-19)28-20-11-7-4-8-12-20/h3-17,22,26H,1-2H3,(H,24,27)/t17-,22+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Inhibitory activity tested against Human Neuropeptide Y2 Receptor. |
J Med Chem 44: 2344-56 (2001)
BindingDB Entry DOI: 10.7270/Q2DV1J56 |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50101536
(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)Show SMILES C[C@H]([C@H](O)c1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C23H24N2O3/c1-17(22(26)18-9-5-3-6-10-18)25(2)23(27)24-19-13-15-21(16-14-19)28-20-11-7-4-8-12-20/h3-17,22,26H,1-2H3,(H,24,27)/t17-,22+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Inhibitory activity tested against Human Neuropeptide Y1 Receptor. |
J Med Chem 44: 2344-56 (2001)
BindingDB Entry DOI: 10.7270/Q2DV1J56 |
More data for this Ligand-Target Pair | |