Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 370.5 BDBM50266078

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Cavia porcellus)	BDBM50266078 ((S)-4-(4-(dimethylamino)benzylthio)-2-((S)-3-merca...) Show SMILES C[C@H](CS)C(=O)N[C@@H](CCSCc1ccc(cc1)N(C)C)C(O)=O |r| Show InChI InChI=1S/C17H26N2O3S2/c1-12(10-23)16(20)18-15(17(21)22)8-9-24-11-13-4-6-14(7-5-13)19(2)3/h4-7,12,15,23H,8-11H2,1-3H3,(H,18,20)(H,21,22)/t12-,15+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Santen Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 production				Bioorg Med Chem Lett 19: 442-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.042 BindingDB Entry DOI: 10.7270/Q20K28FC
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