Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50266211
((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-ph...)Show SMILES C[C@H](CS)C(=O)N[C@@H](CSCc1ccc(Oc2ccccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C20H23NO4S2/c1-14(11-26)19(22)21-18(20(23)24)13-27-12-15-7-9-17(10-8-15)25-16-5-3-2-4-6-16/h2-10,14,18,26H,11-13H2,1H3,(H,21,22)(H,23,24)/t14-,18+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Santen Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLC |
Bioorg Med Chem Lett 19: 442-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.042 BindingDB Entry DOI: 10.7270/Q20K28FC |
More data for this Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Cavia porcellus) | BDBM50266211
((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-ph...)Show SMILES C[C@H](CS)C(=O)N[C@@H](CSCc1ccc(Oc2ccccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C20H23NO4S2/c1-14(11-26)19(22)21-18(20(23)24)13-27-12-15-7-9-17(10-8-15)25-16-5-3-2-4-6-16/h2-10,14,18,26H,11-13H2,1H3,(H,21,22)(H,23,24)/t14-,18+/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Santen Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 production |
Bioorg Med Chem Lett 19: 442-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.042 BindingDB Entry DOI: 10.7270/Q20K28FC |
More data for this Ligand-Target Pair | |