Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 439.5 BDBM50395788

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50395788 (CHEMBL2164846) Show SMILES C[C@H](N[C@@H](Cc1ccccc1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1)c1ccccn1 |r| Show InChI InChI=1S/C26H25N5O2/c1-18(22-9-5-6-12-28-22)30-23(15-19-7-3-2-4-8-19)26(33)31-24-16-21(17-29-25(24)32)20-10-13-27-14-11-20/h2-14,16-18,23,30H,15H2,1H3,(H,29,32)(H,31,33)/t18-,23-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation after 1 hr by scintillation counting				Bioorg Med Chem Lett 22: 6218-23 (2012) Article DOI: 10.1016/j.bmcl.2012.08.015 BindingDB Entry DOI: 10.7270/Q2CN751R
					More data for this Ligand-Target Pair