Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 405.8 BDBM378693

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM378693 (US10266526, Compound 831 | rel-N-{1-[(1S)-1-[2-chl...) Show SMILES C[C@H](N1CC(C1)NC(=O)c1cn(nn1)C1CC1)c1cccc(OCCO)c1Cl |r| Show InChI InChI=1S/C19H24ClN5O3/c1-12(15-3-2-4-17(18(15)20)28-8-7-26)24-9-13(10-24)21-19(27)16-11-25(23-22-16)14-5-6-14/h2-4,11-14,26H,5-10H2,1H3,(H,21,27)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	57.8	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...				Bioorg Med Chem 14: 7241-57 (2006) BindingDB Entry DOI: 10.7270/Q2DJ5HX2
					More data for this Ligand-Target Pair