Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50285633
((R)-3-Benzyl-N-((S)-1-carboxy-ethyl)-succinamic ac...)Show SMILES C[C@H](NC(=O)[C@@H](CC(O)=O)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C14H17NO5/c1-9(14(19)20)15-13(18)11(8-12(16)17)7-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/t9-,11+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007 BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50285633
((R)-3-Benzyl-N-((S)-1-carboxy-ethyl)-succinamic ac...)Show SMILES C[C@H](NC(=O)[C@@H](CC(O)=O)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C14H17NO5/c1-9(14(19)20)15-13(18)11(8-12(16)17)7-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/t9-,11+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory activity against recombinant human Leukotriene A4 hydrolase |
Bioorg Med Chem Lett 5: 2517-2522 (1995)
Article DOI: 10.1016/0960-894X(95)00441-U BindingDB Entry DOI: 10.7270/Q2959J1M |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50285633
((R)-3-Benzyl-N-((S)-1-carboxy-ethyl)-succinamic ac...)Show SMILES C[C@H](NC(=O)[C@@H](CC(O)=O)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C14H17NO5/c1-9(14(19)20)15-13(18)11(8-12(16)17)7-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/t9-,11+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory activity against rabbit lung angiotensin-converting enzyme(ACE) |
Bioorg Med Chem Lett 5: 2517-2522 (1995)
Article DOI: 10.1016/0960-894X(95)00441-U BindingDB Entry DOI: 10.7270/Q2959J1M |
More data for this Ligand-Target Pair | |