Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM50443356
(CHEMBL3086032)Show SMILES C[C@H](NC(=O)[C@@H]1CC[C@H](C[C@H]1c1ccc(Br)cc1)N1CCOCC1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H30BrFN2O2/c1-17(18-4-8-21(27)9-5-18)28-25(30)23-11-10-22(29-12-14-31-15-13-29)16-24(23)19-2-6-20(26)7-3-19/h2-9,17,22-24H,10-16H2,1H3,(H,28,30)/t17-,22+,23+,24-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by fluorescence assay |
Bioorg Med Chem Lett 23: 6228-33 (2013)
Article DOI: 10.1016/j.bmcl.2013.09.094 BindingDB Entry DOI: 10.7270/Q2DZ09Q4 |
More data for this Ligand-Target Pair | |
Lysosomal Pro-X carboxypeptidase
(Mus musculus) | BDBM50443356
(CHEMBL3086032)Show SMILES C[C@H](NC(=O)[C@@H]1CC[C@H](C[C@H]1c1ccc(Br)cc1)N1CCOCC1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H30BrFN2O2/c1-17(18-4-8-21(27)9-5-18)28-25(30)23-11-10-22(29-12-14-31-15-13-29)16-24(23)19-2-6-20(26)7-3-19/h2-9,17,22-24H,10-16H2,1H3,(H,28,30)/t17-,22+,23+,24-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by fluorescence assay |
Bioorg Med Chem Lett 23: 6228-33 (2013)
Article DOI: 10.1016/j.bmcl.2013.09.094 BindingDB Entry DOI: 10.7270/Q2DZ09Q4 |
More data for this Ligand-Target Pair | |