Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 370.9 BDBM50361778

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50361778 (CHEMBL1938514) Show SMILES C[C@H](NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H27ClN2O/c1-17(18-7-9-21(23)10-8-18)24-22(26)13-16-25-14-11-20(12-15-25)19-5-3-2-4-6-19/h2-10,17,20H,11-16H2,1H3,(H,24,26)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assay				Bioorg Med Chem Lett 22: 658-65 (2011) Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50
					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Mus musculus)	BDBM50361778 (CHEMBL1938514) Show SMILES C[C@H](NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H27ClN2O/c1-17(18-7-9-21(23)10-8-18)24-22(26)13-16-25-14-11-20(12-15-25)19-5-3-2-4-6-19/h2-10,17,20H,11-16H2,1H3,(H,24,26)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assay				Bioorg Med Chem Lett 22: 658-65 (2011) Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50
					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Mus musculus)	BDBM50361778 (CHEMBL1938514) Show SMILES C[C@H](NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H27ClN2O/c1-17(18-7-9-21(23)10-8-18)24-22(26)13-16-25-14-11-20(12-15-25)19-5-3-2-4-6-19/h2-10,17,20H,11-16H2,1H3,(H,24,26)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PrCP-mediated conversion of Ang3 to Ang(2-7) in mouse plasma				Bioorg Med Chem Lett 22: 658-65 (2011) Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50
					More data for this Ligand-Target Pair