Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM50361751
(CHEMBL1938486)Show SMILES C[C@H](NC(=O)CCN1CCC(CC1)c1nc(no1)-c1ccccn1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C23H26FN5O2/c1-16(17-5-7-19(24)8-6-17)26-21(30)11-15-29-13-9-18(10-14-29)23-27-22(28-31-23)20-4-2-3-12-25-20/h2-8,12,16,18H,9-11,13-15H2,1H3,(H,26,30)/t16-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 313 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assay |
Bioorg Med Chem Lett 22: 658-65 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50 |
More data for this Ligand-Target Pair | |
Lysosomal Pro-X carboxypeptidase
(Mus musculus) | BDBM50361751
(CHEMBL1938486)Show SMILES C[C@H](NC(=O)CCN1CCC(CC1)c1nc(no1)-c1ccccn1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C23H26FN5O2/c1-16(17-5-7-19(24)8-6-17)26-21(30)11-15-29-13-9-18(10-14-29)23-27-22(28-31-23)20-4-2-3-12-25-20/h2-8,12,16,18H,9-11,13-15H2,1H3,(H,26,30)/t16-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 348 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PrCP-mediated conversion of Ang3 to Ang(2-7) in mouse plasma |
Bioorg Med Chem Lett 22: 658-65 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50 |
More data for this Ligand-Target Pair | |