Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 464.3 BDBM50364392

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50364392 (CHEMBL1950308) Show SMILES C[C@H](NC(=O)CCN1CCN(CC1)c1ccccc1F)c1nc2cc(Cl)c(Cl)cc2[nH]1 |r| Show InChI InChI=1S/C22H24Cl2FN5O/c1-14(22-27-18-12-15(23)16(24)13-19(18)28-22)26-21(31)6-7-29-8-10-30(11-9-29)20-5-3-2-4-17(20)25/h2-5,12-14H,6-11H2,1H3,(H,26,31)(H,27,28)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assay				Bioorg Med Chem Lett 22: 1774-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.064 BindingDB Entry DOI: 10.7270/Q27H1K28
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