Found 5 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50071162
(4-((S)-1-Carboxy-ethylamino)-benzoic acid | CHEMBL...)Show InChI InChI=1S/C10H11NO4/c1-6(9(12)13)11-8-4-2-7(3-5-8)10(14)15/h2-6,11H,1H3,(H,12,13)(H,14,15)/t6-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells. |
Bioorg Med Chem Lett 8: 1985-90 (1999)
BindingDB Entry DOI: 10.7270/Q2K35V5D |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50071162
(4-((S)-1-Carboxy-ethylamino)-benzoic acid | CHEMBL...)Show InChI InChI=1S/C10H11NO4/c1-6(9(12)13)11-8-4-2-7(3-5-8)10(14)15/h2-6,11H,1H3,(H,12,13)(H,14,15)/t6-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.95E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells. |
Bioorg Med Chem Lett 8: 1985-90 (1999)
BindingDB Entry DOI: 10.7270/Q2K35V5D |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50071162
(4-((S)-1-Carboxy-ethylamino)-benzoic acid | CHEMBL...)Show InChI InChI=1S/C10H11NO4/c1-6(9(12)13)11-8-4-2-7(3-5-8)10(14)15/h2-6,11H,1H3,(H,12,13)(H,14,15)/t6-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.39E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells. |
Bioorg Med Chem Lett 8: 1985-90 (1999)
BindingDB Entry DOI: 10.7270/Q2K35V5D |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 8
(Homo sapiens (Human)) | BDBM50071162
(4-((S)-1-Carboxy-ethylamino)-benzoic acid | CHEMBL...)Show InChI InChI=1S/C10H11NO4/c1-6(9(12)13)11-8-4-2-7(3-5-8)10(14)15/h2-6,11H,1H3,(H,12,13)(H,14,15)/t6-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description In vitro antagonist activity at recombinant Metabotropic glutamate receptor 8 expressed in RGT cells. |
Bioorg Med Chem Lett 8: 1985-90 (1999)
BindingDB Entry DOI: 10.7270/Q2K35V5D |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50071162
(4-((S)-1-Carboxy-ethylamino)-benzoic acid | CHEMBL...)Show InChI InChI=1S/C10H11NO4/c1-6(9(12)13)11-8-4-2-7(3-5-8)10(14)15/h2-6,11H,1H3,(H,12,13)(H,14,15)/t6-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 4 expressed in RGT cells. |
Bioorg Med Chem Lett 8: 1985-90 (1999)
BindingDB Entry DOI: 10.7270/Q2K35V5D |
More data for this Ligand-Target Pair | |