Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 342.4 BDBM50266105

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Cavia porcellus)	BDBM50266105 ((R)-3-(4-(dimethylamino)benzylthio)-2-((S)-2-merca...) Show SMILES C[C@H](S)C(=O)N[C@@H](CSCc1ccc(cc1)N(C)C)C(O)=O |r| Show InChI InChI=1S/C15H22N2O3S2/c1-10(21)14(18)16-13(15(19)20)9-22-8-11-4-6-12(7-5-11)17(2)3/h4-7,10,13,21H,8-9H2,1-3H3,(H,16,18)(H,19,20)/t10-,13-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Santen Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 production				Bioorg Med Chem Lett 19: 442-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.042 BindingDB Entry DOI: 10.7270/Q20K28FC
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