Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine receptor H3
(Macaca mulatta (Rhesus macaque)) | BDBM50442626
(CHEMBL2441642)Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)CC2CCCC2)c(C)c1 |r| Show InChI InChI=1S/C23H35N3O/c1-17-14-20(25-13-11-21(16-25)26-12-5-6-18(26)2)9-10-22(17)24-23(27)15-19-7-3-4-8-19/h9-10,14,18-19,21H,3-8,11-13,15-16H2,1-2H3,(H,24,27)/t18-,21-/m0/s1 | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.850 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi US
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 23: 6141-5 (2013)
Article DOI: 10.1016/j.bmcl.2013.09.006 BindingDB Entry DOI: 10.7270/Q24T6KT6 |
More data for this Ligand-Target Pair | |
Histamine receptor H3
(Macaca mulatta (Rhesus macaque)) | BDBM50442626
(CHEMBL2441642)Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)CC2CCCC2)c(C)c1 |r| Show InChI InChI=1S/C23H35N3O/c1-17-14-20(25-13-11-21(16-25)26-12-5-6-18(26)2)9-10-22(17)24-23(27)15-19-7-3-4-8-19/h9-10,14,18-19,21H,3-8,11-13,15-16H2,1-2H3,(H,24,27)/t18-,21-/m0/s1 | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi US
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 23: 6141-5 (2013)
Article DOI: 10.1016/j.bmcl.2013.09.006 BindingDB Entry DOI: 10.7270/Q24T6KT6 |
More data for this Ligand-Target Pair | |