Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 348.5 BDBM247468

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247468 (US9453023, 27) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NS(=O)(=O)C2CC2)cc1 |r| Show InChI InChI=1S/C19H28N2O2S/c1-14-3-2-12-21(14)18-9-6-16(13-18)15-4-7-17(8-5-15)20-24(22,23)19-10-11-19/h4-5,7-8,14,16,18-20H,2-3,6,9-13H2,1H3/t14-,16-,18?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
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