Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 382.5 BDBM247442

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247442 (US9453023, 1) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(cc1)N1CCC2(CCOCC2)C1=O |r| Show InChI InChI=1S/C24H34N2O2/c1-18-3-2-13-25(18)22-9-6-20(17-22)19-4-7-21(8-5-19)26-14-10-24(23(26)27)11-15-28-16-12-24/h4-5,7-8,18,20,22H,2-3,6,9-17H2,1H3/t18-,20-,22?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair