Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 513.5 BDBM376620

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM376620 (US9918990, Example 70) Show SMILES C[C@H]1CN(CCn2c3ccc(c(Oc4ccccc4)c3[nH]c2=O)-c2cn(C)c(=O)c3[nH]ccc23)C[C@@H](C)O1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center					Assay Description BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...				J Med Chem 50: 3906-20 (2007) BindingDB Entry DOI: 10.7270/Q28054XR
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM376620 (US9918990, Example 70) Show SMILES C[C@H]1CN(CCn2c3ccc(c(Oc4ccccc4)c3[nH]c2=O)-c2cn(C)c(=O)c3[nH]ccc23)C[C@@H](C)O1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center					Assay Description BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...				J Med Chem 50: 3906-20 (2007) BindingDB Entry DOI: 10.7270/Q28054XR
					More data for this Ligand-Target Pair