Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM101404
(US9695152, 25 | US9695152, 26)Show SMILES C[C@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc(NC2CN(C2)C(=O)c2cnccc2C)c1 |r| Show InChI InChI=1S/C24H22ClN5O2/c1-14-5-6-26-11-22(14)23(31)29-12-18(13-29)28-17-8-19(10-27-9-17)30-15(2)21-7-16(25)3-4-20(21)24(30)32/h3-11,15,18,28H,12-13H2,1-2H3/t15-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695152 (2017)
BindingDB Entry DOI: 10.7270/Q2FN14BQ |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM101404
(US9695152, 25 | US9695152, 26)Show SMILES C[C@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc(NC2CN(C2)C(=O)c2cnccc2C)c1 |r| Show InChI InChI=1S/C24H22ClN5O2/c1-14-5-6-26-11-22(14)23(31)29-12-18(13-29)28-17-8-19(10-27-9-17)30-15(2)21-7-16(25)3-4-20(21)24(30)32/h3-11,15,18,28H,12-13H2,1-2H3/t15-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 1.91E+3 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695152 (2017)
BindingDB Entry DOI: 10.7270/Q2FN14BQ |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM101404
(US9695152, 25 | US9695152, 26)Show SMILES C[C@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc(NC2CN(C2)C(=O)c2cnccc2C)c1 |r| Show InChI InChI=1S/C24H22ClN5O2/c1-14-5-6-26-11-22(14)23(31)29-12-18(13-29)28-17-8-19(10-27-9-17)30-15(2)21-7-16(25)3-4-20(21)24(30)32/h3-11,15,18,28H,12-13H2,1-2H3/t15-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695152 (2017)
BindingDB Entry DOI: 10.7270/Q2FN14BQ |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM101404
(US9695152, 25 | US9695152, 26)Show SMILES C[C@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc(NC2CN(C2)C(=O)c2cnccc2C)c1 |r| Show InChI InChI=1S/C24H22ClN5O2/c1-14-5-6-26-11-22(14)23(31)29-12-18(13-29)28-17-8-19(10-27-9-17)30-15(2)21-7-16(25)3-4-20(21)24(30)32/h3-11,15,18,28H,12-13H2,1-2H3/t15-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 4.36E+3 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695152 (2017)
BindingDB Entry DOI: 10.7270/Q2FN14BQ |
More data for this Ligand-Target Pair | |