Found 13 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
DNA polymerase kappa
(Homo sapiens (Human)) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po... |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
DNA polymerase nu
(Homo sapiens (Human)) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of C-terminal-His6-tagged human pol nu expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(d... |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
DNA polymerase iota
(Mus musculus) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ... |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
DNA polymerase delta catalytic subunit
(Homo sapiens (Human)) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
DNA polymerase beta
(Rattus norvegicus) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of rat DNA polymerase beta expressed in Escherichia coli JMpbeta5 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)1... |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
DNA nucleotidylexotransferase
(Bos taurus) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of calf TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 mins |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
Probable maltase-glucoamylase 2
(Homo sapiens) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hebei University
Curated by ChEMBL
| Assay Description Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl glycoside as substrate treated 20 mins post substrate addition measured for 1 mi... |
J Nat Prod 80: 2199-2203 (2017)
Article DOI: 10.1021/acs.jnatprod.7b00032 BindingDB Entry DOI: 10.7270/Q20P12MS |
More data for this Ligand-Target Pair | |
Polynucleotide kinase
(Enterobacteria phage T4) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of T4 arnN8l pseT 1 polynucleotide kinase assessed as inhibition of Salmon sperm DNA phosphorylation using [gamma32P]ATP by liquid scintil... |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
DNA-directed DNA polymerase
(Enterobacteria phage T4) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of T4 bacteriophage DNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
DNA-directed DNA/RNA polymerase mu
(Homo sapiens (Human)) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of human His-tagged recombinant DNA polymerase mu expressed in Escherichia coli BL21 assessed as inhibition of incorporation of dTTP into ... |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
DNA polymerase lambda
(Homo sapiens (Human)) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of human recombinant His-tagged DNA polymerase lambda expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p... |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
Deoxyribonuclease-1
(Bos taurus) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of bovine deoxyribonuclease 1 using [3H]-labelled DNA after 30 mins by agorose gel electrophoresis |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Mus musculus) | BDBM50379293
(CHEMBL2011648)Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo
Curated by ChEMBL
| Assay Description Inhibition of mouse IMP dehydrogenase 2 |
J Nat Prod 75: 135-41 (2012)
Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG |
More data for this Ligand-Target Pair | |