Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 362.4 BDBM50305754

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50305754 (4-(1-(6-(1H-imidazol-1-yl)pyridazin-3-yl)piperidin...) Show SMILES C1C=NC2C=CC=C(OC3CCN(CC3)c3ccc(nn3)-n3ccnc3)C12 |c:1,4,t:6| Show InChI InChI=1S/C20H22N6O/c1-2-17-16(6-9-22-17)18(3-1)27-15-7-11-25(12-8-15)19-4-5-20(24-23-19)26-13-10-21-14-26/h1-5,9-10,13-17H,6-8,11-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of SCD1 in rat liver microsomes				Bioorg Med Chem Lett 20: 499-502 (2010) Article DOI: 10.1016/j.bmcl.2009.11.111 BindingDB Entry DOI: 10.7270/Q26H4HH3
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