Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 201.2 BDBM50110262

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit beta-4 (Rattus norvegicus (Rat))	BDBM50110262 (2-Pyridazin-4-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...) Show SMILES C1CC2N[C@H]1CCC=C2c1ccnnc1 |c:8,THB:9:8:3:1.0| Show InChI InChI=1S/C12H15N3/c1-2-10-4-5-12(15-10)11(3-1)9-6-7-13-14-8-9/h3,6-8,10,12,15H,1-2,4-5H2/t10-,12?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal gland				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50110262 (2-Pyridazin-4-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...) Show SMILES C1CC2N[C@H]1CCC=C2c1ccnnc1 |c:8,THB:9:8:3:1.0| Show InChI InChI=1S/C12H15N3/c1-2-10-4-5-12(15-10)11(3-1)9-6-7-13-14-8-9/h3,6-8,10,12,15H,1-2,4-5H2/t10-,12?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to subtype Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligand in rat brain				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50110262 (2-Pyridazin-4-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...) Show SMILES C1CC2N[C@H]1CCC=C2c1ccnnc1 |c:8,THB:9:8:3:1.0| Show InChI InChI=1S/C12H15N3/c1-2-10-4-5-12(15-10)11(3-1)9-6-7-13-14-8-9/h3,6-8,10,12,15H,1-2,4-5H2/t10-,12?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to Nicotinic acetylcholine receptor alpha4-beta2 using +/-[3H]epibatidine as radioligand in rat brain				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair