Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 241.3 BDBM50062780

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50062780 (1-(1,3,4,8b-Tetrahydro-2H-biphenylen-4a-yl)-piperi...) Show SMILES C1CCN(CC1)C12CCCCC1c1ccccc21 Show InChI InChI=1S/C17H23N/c1-6-12-18(13-7-1)17-11-5-4-10-16(17)14-8-2-3-9-15(14)17/h2-3,8-9,16H,1,4-7,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago 60607-7061 Curated by ChEMBL					Assay Description Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellum				J Med Chem 41: 468-77 (1998) Article DOI: 10.1021/jm970059p BindingDB Entry DOI: 10.7270/Q27W6CW7
					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50062780 (1-(1,3,4,8b-Tetrahydro-2H-biphenylen-4a-yl)-piperi...) Show SMILES C1CCN(CC1)C12CCCCC1c1ccccc21 Show InChI InChI=1S/C17H23N/c1-6-12-18(13-7-1)17-11-5-4-10-16(17)14-8-2-3-9-15(14)17/h2-3,8-9,16H,1,4-7,10-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago 60607-7061 Curated by ChEMBL					Assay Description Inhibition of [3H]-TCP binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellum				J Med Chem 41: 468-77 (1998) Article DOI: 10.1021/jm970059p BindingDB Entry DOI: 10.7270/Q27W6CW7
					More data for this Ligand-Target Pair