Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 3A/3B/3C/3D/3E
(Homo sapiens (Human)) | BDBM50408171
(CHEMBL53490)Show InChI InChI=1S/C14H15N5/c1-3-11-13(16-5-1)19-8-2-4-12(19)14(17-11)18-9-6-15-7-10-18/h1-5,8,15H,6-7,9-10H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50408171
(CHEMBL53490)Show InChI InChI=1S/C14H15N5/c1-3-11-13(16-5-1)19-8-2-4-12(19)14(17-11)18-9-6-15-7-10-18/h1-5,8,15H,6-7,9-10H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 64.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor was measured using [3H]8-OH-DPAT as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat)) | BDBM50408171
(CHEMBL53490)Show InChI InChI=1S/C14H15N5/c1-3-11-13(16-5-1)19-8-2-4-12(19)14(17-11)18-9-6-15-7-10-18/h1-5,8,15H,6-7,9-10H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity towards 5-hydroxytryptamine 1B receptor was measured using [3H]5-HT as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50408171
(CHEMBL53490)Show InChI InChI=1S/C14H15N5/c1-3-11-13(16-5-1)19-8-2-4-12(19)14(17-11)18-9-6-15-7-10-18/h1-5,8,15H,6-7,9-10H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 269 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity against 5-Hydroxytryptamine 2C Receptor was measured using [3H]N-methyl-mesulergine as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Sus scrofa) | BDBM50408171
(CHEMBL53490)Show InChI InChI=1S/C14H15N5/c1-3-11-13(16-5-1)19-8-2-4-12(19)14(17-11)18-9-6-15-7-10-18/h1-5,8,15H,6-7,9-10H2 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor was measured using [3H]5-HT as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(BOVINE) | BDBM50408171
(CHEMBL53490)Show InChI InChI=1S/C14H15N5/c1-3-11-13(16-5-1)19-8-2-4-12(19)14(17-11)18-9-6-15-7-10-18/h1-5,8,15H,6-7,9-10H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor was measured using [3H]ketanserin as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |