Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
D(1A)/D(2) dopamine receptor
(BOVINE) | BDBM50017045
(8-Phenyl-1,2,3,4-tetrahydro-isoquinoline | CHEMBL2...)Show InChI InChI=1S/C15H15N/c1-2-5-12(6-3-1)14-8-4-7-13-9-10-16-11-15(13)14/h1-8,16H,9-11H2 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of [3H]haloperidol binding to Dopamine receptor in calf caudate nuclei. |
J Med Chem 23: 977-80 (1980)
BindingDB Entry DOI: 10.7270/Q2N3005S |
More data for this Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(RAT) | BDBM50017045
(8-Phenyl-1,2,3,4-tetrahydro-isoquinoline | CHEMBL2...)Show InChI InChI=1S/C15H15N/c1-2-5-12(6-3-1)14-8-4-7-13-9-10-16-11-15(13)14/h1-8,16H,9-11H2 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle& Co.
Curated by ChEMBL
| Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor |
J Med Chem 32: 1242-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CR5TXJ |
More data for this Ligand-Target Pair | |
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM50017045
(8-Phenyl-1,2,3,4-tetrahydro-isoquinoline | CHEMBL2...)Show InChI InChI=1S/C15H15N/c1-2-5-12(6-3-1)14-8-4-7-13-9-10-16-11-15(13)14/h1-8,16H,9-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle& Co.
Curated by ChEMBL
| Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor |
J Med Chem 32: 1242-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CR5TXJ |
More data for this Ligand-Target Pair | |
D(1A)/D(2) dopamine receptor
(BOVINE) | BDBM50017045
(8-Phenyl-1,2,3,4-tetrahydro-isoquinoline | CHEMBL2...)Show InChI InChI=1S/C15H15N/c1-2-5-12(6-3-1)14-8-4-7-13-9-10-16-11-15(13)14/h1-8,16H,9-11H2 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of [3H]dopamine binding to Dopamine receptor in calf caudate nuclei. |
J Med Chem 23: 977-80 (1980)
BindingDB Entry DOI: 10.7270/Q2N3005S |
More data for this Ligand-Target Pair | |