Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cathepsin D
(Homo sapiens (Human)) | BDBM50328031
(CHEMBL1258119 | N-((2S,3R)-4-(1-(3-acetyl-5-tert-b...)Show SMILES CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(CCCCC1)c1cc(cc(c1)C(C)(C)C)C(C)=O |r| Show InChI InChI=1S/C30H40F2N2O3/c1-19(35)22-14-23(29(3,4)5)16-24(15-22)30(9-7-6-8-10-30)33-18-28(37)27(34-20(2)36)13-21-11-25(31)17-26(32)12-21/h11-12,14-17,27-28,33,37H,6-10,13,18H2,1-5H3,(H,34,36)/t27-,28+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of cathepsin D |
Bioorg Med Chem Lett 20: 6034-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.070
BindingDB Entry DOI: 10.7270/Q2XK8FSK |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM50328031
(CHEMBL1258119 | N-((2S,3R)-4-(1-(3-acetyl-5-tert-b...)Show SMILES CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(CCCCC1)c1cc(cc(c1)C(C)(C)C)C(C)=O |r| Show InChI InChI=1S/C30H40F2N2O3/c1-19(35)22-14-23(29(3,4)5)16-24(15-22)30(9-7-6-8-10-30)33-18-28(37)27(34-20(2)36)13-21-11-25(31)17-26(32)12-21/h11-12,14-17,27-28,33,37H,6-10,13,18H2,1-5H3,(H,34,36)/t27-,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of BACE1 |
Bioorg Med Chem Lett 20: 6034-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.070
BindingDB Entry DOI: 10.7270/Q2XK8FSK |
More data for this
Ligand-Target Pair | |