Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 655.7 BDBM50511319

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocyte-stimulating hormone receptor (Mus musculus)	BDBM50511319 (CHEMBL4582657) Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C29H45N13O5/c1-17(43)39-23(14-19-15-35-16-38-19)27(47)42-22(13-18-7-3-2-4-8-18)26(46)41-21(10-6-12-37-29(33)34)25(45)40-20(24(30)44)9-5-11-36-28(31)32/h2-4,7-8,15-16,20-23H,5-6,9-14H2,1H3,(H2,30,44)(H,35,38)(H,39,43)(H,40,45)(H,41,46)(H,42,47)(H4,31,32,36)(H4,33,34,37)/t20-,21-,22+,23-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...				ACS Med Chem Lett 11: 272-277 (2020) Article DOI: 10.1021/acsmedchemlett.9b00198 BindingDB Entry DOI: 10.7270/Q2QV3QTB
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Mus musculus)	BDBM50511319 (CHEMBL4582657) Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C29H45N13O5/c1-17(43)39-23(14-19-15-35-16-38-19)27(47)42-22(13-18-7-3-2-4-8-18)26(46)41-21(10-6-12-37-29(33)34)25(45)40-20(24(30)44)9-5-11-36-28(31)32/h2-4,7-8,15-16,20-23H,5-6,9-14H2,1H3,(H2,30,44)(H,35,38)(H,39,43)(H,40,45)(H,41,46)(H,42,47)(H4,31,32,36)(H4,33,34,37)/t20-,21-,22+,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...				ACS Med Chem Lett 11: 272-277 (2020) Article DOI: 10.1021/acsmedchemlett.9b00198 BindingDB Entry DOI: 10.7270/Q2QV3QTB
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Mus musculus)	BDBM50511319 (CHEMBL4582657) Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C29H45N13O5/c1-17(43)39-23(14-19-15-35-16-38-19)27(47)42-22(13-18-7-3-2-4-8-18)26(46)41-21(10-6-12-37-29(33)34)25(45)40-20(24(30)44)9-5-11-36-28(31)32/h2-4,7-8,15-16,20-23H,5-6,9-14H2,1H3,(H2,30,44)(H,35,38)(H,39,43)(H,40,45)(H,41,46)(H,42,47)(H4,31,32,36)(H4,33,34,37)/t20-,21-,22+,23-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...				ACS Med Chem Lett 11: 272-277 (2020) Article DOI: 10.1021/acsmedchemlett.9b00198 BindingDB Entry DOI: 10.7270/Q2QV3QTB
					More data for this Ligand-Target Pair