Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM32466
(piperazine amide, 4m)Show SMILES CC(=O)N1CCN(CC1)c1c(Cl)cccc1NC(=O)c1ccc(Br)o1 Show InChI InChI=1S/C17H17BrClN3O3/c1-11(23)21-7-9-22(10-8-21)16-12(19)3-2-4-13(16)20-17(24)14-5-6-15(18)25-14/h2-6H,7-10H2,1H3,(H,20,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
| Assay Description
Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a... |
Bioorg Med Chem Lett 19: 3344-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.086
BindingDB Entry DOI: 10.7270/Q2ST7N67 |
More data for this
Ligand-Target Pair | |
Isoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402]
(Homo sapiens (Human)) | BDBM32466
(piperazine amide, 4m)Show SMILES CC(=O)N1CCN(CC1)c1c(Cl)cccc1NC(=O)c1ccc(Br)o1 Show InChI InChI=1S/C17H17BrClN3O3/c1-11(23)21-7-9-22(10-8-21)16-12(19)3-2-4-13(16)20-17(24)14-5-6-15(18)25-14/h2-6H,7-10H2,1H3,(H,20,24) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 810 | n/a | n/a | n/a | n/a | 7.0 | 22 |
The Scripps Research Institute
| Assay Description
Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a... |
Bioorg Med Chem Lett 19: 3344-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.086
BindingDB Entry DOI: 10.7270/Q2ST7N67 |
More data for this
Ligand-Target Pair | |