Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140484
(1-{6-[(1-Benzyl-piperidin-4-yl)-((E)-3-phenyl-ally...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C\C=C\c1ccccc1)C1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C31H35N3O/c1-25(35)33-22-16-28-14-15-30(23-31(28)33)34(19-8-13-26-9-4-2-5-10-26)29-17-20-32(21-18-29)24-27-11-6-3-7-12-27/h2-15,23,29H,16-22,24H2,1H3/b13-8+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]-PYY from human NPYY2 receptor |
Bioorg Med Chem Lett 24: 430-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.061 BindingDB Entry DOI: 10.7270/Q2H133HQ |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140484
(1-{6-[(1-Benzyl-piperidin-4-yl)-((E)-3-phenyl-ally...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C\C=C\c1ccccc1)C1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C31H35N3O/c1-25(35)33-22-16-28-14-15-30(23-31(28)33)34(19-8-13-26-9-4-2-5-10-26)29-17-20-32(21-18-29)24-27-11-6-3-7-12-27/h2-15,23,29H,16-22,24H2,1H3/b13-8+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057 BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this Ligand-Target Pair | |