Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50445681
(CHEMBL3104217)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ncc[nH]1 Show InChI InChI=1S/C28H31N5O2/c1-21(34)32-18-11-23-7-8-25(19-26(23)32)33(28(35)10-9-27-29-14-15-30-27)24-12-16-31(17-13-24)20-22-5-3-2-4-6-22/h2-10,14-15,19,24H,11-13,16-18,20H2,1H3,(H,29,30)/b10-9+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]-PYY from human NPYY2 receptor |
Bioorg Med Chem Lett 24: 430-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.061 BindingDB Entry DOI: 10.7270/Q2H133HQ |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140493
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\C1N=CC=N1 |c:35,37| Show InChI InChI=1S/C28H31N5O2/c1-21(34)32-18-11-23-7-8-25(19-26(23)32)33(28(35)10-9-27-29-14-15-30-27)24-12-16-31(17-13-24)20-22-5-3-2-4-6-22/h2-10,14-15,19,24,27H,11-13,16-18,20H2,1H3/b10-9+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057 BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this Ligand-Target Pair | |