Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140474
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C32H32F3N3O2/c1-23(39)37-19-14-26-11-12-29(21-30(26)37)38(28-15-17-36(18-16-28)22-25-6-3-2-4-7-25)31(40)13-10-24-8-5-9-27(20-24)32(33,34)35/h2-13,20-21,28H,14-19,22H2,1H3/b13-10+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]-PYY from human NPYY2 receptor |
Bioorg Med Chem Lett 24: 430-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.061 BindingDB Entry DOI: 10.7270/Q2H133HQ |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140474
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C32H32F3N3O2/c1-23(39)37-19-14-26-11-12-29(21-30(26)37)38(28-15-17-36(18-16-28)22-25-6-3-2-4-7-25)31(40)13-10-24-8-5-9-27(20-24)32(33,34)35/h2-13,20-21,28H,14-19,22H2,1H3/b13-10+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057 BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this Ligand-Target Pair | |