Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 493.6 BDBM50140473

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50140473 ((E)-4-Phenyl-but-3-enoic acid (1-acetyl-2,3-dihydr...) Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)C\C=C\c1ccccc1 Show InChI InChI=1S/C32H35N3O2/c1-25(36)34-22-17-28-15-16-30(23-31(28)34)35(32(37)14-8-13-26-9-4-2-5-10-26)29-18-20-33(21-19-29)24-27-11-6-3-7-12-27/h2-13,15-16,23,29H,14,17-22,24H2,1H3/b13-8+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards the NPY Y2 receptor				Bioorg Med Chem Lett 14: 1239-42 (2004) Article DOI: 10.1016/j.bmcl.2003.12.057 BindingDB Entry DOI: 10.7270/Q2M044VK
					More data for this Ligand-Target Pair