Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50179953
(1-[8-(3-aminomethyl-phenyl)-2-chloro-11,12-dihydro...)Show SMILES CC(=O)N1Cc2cc(ccc2CCc2cc(Cl)ccc12)-c1cccc(CN)c1 Show InChI InChI=1S/C24H23ClN2O/c1-16(28)27-15-22-12-20(19-4-2-3-17(11-19)14-26)7-5-18(22)6-8-21-13-23(25)9-10-24(21)27/h2-5,7,9-13H,6,8,14-15,26H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 by SEAP assay |
Bioorg Med Chem Lett 16: 1532-6 (2006)
Article DOI: 10.1016/j.bmcl.2005.12.039 BindingDB Entry DOI: 10.7270/Q2CV4HBV |
More data for this Ligand-Target Pair | |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50179953
(1-[8-(3-aminomethyl-phenyl)-2-chloro-11,12-dihydro...)Show SMILES CC(=O)N1Cc2cc(ccc2CCc2cc(Cl)ccc12)-c1cccc(CN)c1 Show InChI InChI=1S/C24H23ClN2O/c1-16(28)27-15-22-12-20(19-4-2-3-17(11-19)14-26)7-5-18(22)6-8-21-13-23(25)9-10-24(21)27/h2-5,7,9-13H,6,8,14-15,26H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 |
Bioorg Med Chem Lett 16: 1532-6 (2006)
Article DOI: 10.1016/j.bmcl.2005.12.039 BindingDB Entry DOI: 10.7270/Q2CV4HBV |
More data for this Ligand-Target Pair | |