Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50179965
(CHEMBL382624 | N-[3-(5-acetyl-2-chloro-5,6,11,12-t...)Show SMILES CC(=O)N1Cc2cc(ccc2CCc2cc(Cl)ccc12)-c1cccc(NS(C)(=O)=O)c1 Show InChI InChI=1S/C24H23ClN2O3S/c1-16(28)27-15-21-12-19(18-4-3-5-23(14-18)26-31(2,29)30)8-6-17(21)7-9-20-13-22(25)10-11-24(20)27/h3-6,8,10-14,26H,7,9,15H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 |
Bioorg Med Chem Lett 16: 1532-6 (2006)
Article DOI: 10.1016/j.bmcl.2005.12.039 BindingDB Entry DOI: 10.7270/Q2CV4HBV |
More data for this Ligand-Target Pair | |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50179965
(CHEMBL382624 | N-[3-(5-acetyl-2-chloro-5,6,11,12-t...)Show SMILES CC(=O)N1Cc2cc(ccc2CCc2cc(Cl)ccc12)-c1cccc(NS(C)(=O)=O)c1 Show InChI InChI=1S/C24H23ClN2O3S/c1-16(28)27-15-21-12-19(18-4-3-5-23(14-18)26-31(2,29)30)8-6-17(21)7-9-20-13-22(25)10-11-24(20)27/h3-6,8,10-14,26H,7,9,15H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 by SEAP assay |
Bioorg Med Chem Lett 16: 1532-6 (2006)
Article DOI: 10.1016/j.bmcl.2005.12.039 BindingDB Entry DOI: 10.7270/Q2CV4HBV |
More data for this Ligand-Target Pair | |