Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50179956
(1-(2-chloro-8-phenyl-11,12-dihydro-6H-dibenzo[b,f]...)Show SMILES CC(=O)N1Cc2cc(ccc2CCc2cc(Cl)ccc12)-c1ccccc1 Show InChI InChI=1S/C23H20ClNO/c1-16(26)25-15-21-13-19(17-5-3-2-4-6-17)9-7-18(21)8-10-20-14-22(24)11-12-23(20)25/h2-7,9,11-14H,8,10,15H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 |
Bioorg Med Chem Lett 16: 1532-6 (2006)
Article DOI: 10.1016/j.bmcl.2005.12.039 BindingDB Entry DOI: 10.7270/Q2CV4HBV |
More data for this Ligand-Target Pair | |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50179956
(1-(2-chloro-8-phenyl-11,12-dihydro-6H-dibenzo[b,f]...)Show SMILES CC(=O)N1Cc2cc(ccc2CCc2cc(Cl)ccc12)-c1ccccc1 Show InChI InChI=1S/C23H20ClNO/c1-16(26)25-15-21-13-19(17-5-3-2-4-6-17)9-7-18(21)8-10-20-14-22(24)11-12-23(20)25/h2-7,9,11-14H,8,10,15H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 by SEAP assay |
Bioorg Med Chem Lett 16: 1532-6 (2006)
Article DOI: 10.1016/j.bmcl.2005.12.039 BindingDB Entry DOI: 10.7270/Q2CV4HBV |
More data for this Ligand-Target Pair | |