Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM24229
(Benzthiazole compound, 27n | N-(1-{2-[4-(1,3-benzo...)Show SMILES CC(=O)NC1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C22H25N3O2S/c1-16(26)23-18-11-14-25(15-12-18)13-10-17-6-8-19(9-7-17)27-22-24-20-4-2-3-5-21(20)28-22/h2-9,18H,10-15H2,1H3,(H,23,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical
| Assay Description
Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... |
J Med Chem 51: 4150-69 (2008)
Article DOI: 10.1021/jm701575k
BindingDB Entry DOI: 10.7270/Q2GB22CX |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM24229
(Benzthiazole compound, 27n | N-(1-{2-[4-(1,3-benzo...)Show SMILES CC(=O)NC1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C22H25N3O2S/c1-16(26)23-18-11-14-25(15-12-18)13-10-17-6-8-19(9-7-17)27-22-24-20-4-2-3-5-21(20)28-22/h2-9,18H,10-15H2,1H3,(H,23,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical
| Assay Description
Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel. |
J Med Chem 51: 4150-69 (2008)
Article DOI: 10.1021/jm701575k
BindingDB Entry DOI: 10.7270/Q2GB22CX |
More data for this
Ligand-Target Pair | |