Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 656.5 BDBM363386

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM363386 (N-(2-((5-bromo-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-d...) Show SMILES CC(=O)NCCNCc1cc(Br)c(OCc2cccc(c2C)-c2ccc3OCCOc3c2)cc1OCc1cccc(c1)C#N Show InChI InChI=1S/C35H34BrN3O5/c1-23-28(7-4-8-30(23)27-9-10-32-35(17-27)42-14-13-41-32)22-44-34-18-33(43-21-26-6-3-5-25(15-26)19-37)29(16-31(34)36)20-38-11-12-39-24(2)40/h3-10,15-18,38H,11-14,20-22H2,1-2H3,(H,39,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...				US Patent US9850225 (2017) BindingDB Entry DOI: 10.7270/Q2N018TZ
					More data for this Ligand-Target Pair