Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 591.6 BDBM363345

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM363345 (N-(2-((2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobe...) Show SMILES CC(=O)NCCNCc1cc(C)c(OCc2cccc(c2C)-c2ccc3OCCOc3c2)cc1OCc1cccc(c1)C#N Show InChI InChI=1S/C36H37N3O5/c1-24-16-31(21-38-12-13-39-26(3)40)35(43-22-28-7-4-6-27(17-28)20-37)19-34(24)44-23-30-8-5-9-32(25(30)2)29-10-11-33-36(18-29)42-15-14-41-33/h4-11,16-19,38H,12-15,21-23H2,1-3H3,(H,39,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...				US Patent US9850225 (2017) BindingDB Entry DOI: 10.7270/Q2N018TZ
					More data for this Ligand-Target Pair