Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 526.6 BDBM363179

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM363179 (N-(2-((2-((4-fluoro-3-methylbenzyl)oxy)-4-((2-meth...) Show SMILES CC(=O)NCCNCc1ccc(OCc2cccc(c2C)-c2ccccc2)cc1OCc1ccc(F)c(C)c1 Show InChI InChI=1S/C33H35FN2O3/c1-23-18-26(12-15-32(23)34)21-39-33-19-30(14-13-28(33)20-35-16-17-36-25(3)37)38-22-29-10-7-11-31(24(29)2)27-8-5-4-6-9-27/h4-15,18-19,35H,16-17,20-22H2,1-3H3,(H,36,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	624	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...				US Patent US9850225 (2017) BindingDB Entry DOI: 10.7270/Q2N018TZ
					More data for this Ligand-Target Pair