Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 544.6 BDBM363124

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM363124 (N-(2-((4-((2-methyl-[1,1′-biphenyl]-3-yl)met...) Show SMILES CC(=O)NCCNCc1ccc(OCc2cccc(c2C)-c2ccccc2)cc1OCc1ccc2ccccc2c1 Show InChI InChI=1S/C36H36N2O3/c1-26-33(13-8-14-35(26)30-10-4-3-5-11-30)25-40-34-18-17-32(23-37-19-20-38-27(2)39)36(22-34)41-24-28-15-16-29-9-6-7-12-31(29)21-28/h3-18,21-22,37H,19-20,23-25H2,1-2H3,(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...				US Patent US9850225 (2017) BindingDB Entry DOI: 10.7270/Q2N018TZ
					More data for this Ligand-Target Pair