Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 400.2 BDBM50001143

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase alpha catalytic subunit (Homo sapiens (Human))	BDBM50001143 (CHEMBL3236419) Show SMILES CC(=O)NP(S)(=O)OC[C@H]1O[C@@H](n2ccc(N)nc2=O)C(F)(F)[C@@H]1O |r| Show InChI InChI=1S/C11H15F2N4O6PS/c1-5(18)16-24(21,25)22-4-6-8(19)11(12,13)9(23-6)17-3-2-7(14)15-10(17)20/h2-3,6,8-9,19H,4H2,1H3,(H2,14,15,20)(H2,16,18,21,25)/t6-,8-,9-,24?/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human DNA polymerase alpha using dCTP as substrate assessed as single base extension reaction after 2 hrs				Bioorg Med Chem 22: 2133-40 (2014) Article DOI: 10.1016/j.bmc.2014.02.034 BindingDB Entry DOI: 10.7270/Q20866TW
					More data for this Ligand-Target Pair