Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50296311
(4-acetamido-3-(2-hydroxyethoxy)-N-(5-(3-(trifluoro...)Show SMILES CC(=O)Nc1ccc(cc1OCCO)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C22H20F3N3O4S/c1-13(30)27-18-6-5-15(11-19(18)32-8-7-29)20(31)28-21-26-12-17(33-21)10-14-3-2-4-16(9-14)22(23,24)25/h2-6,9,11-12,29H,7-8,10H2,1H3,(H,27,30)(H,26,28,31) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50296311
(4-acetamido-3-(2-hydroxyethoxy)-N-(5-(3-(trifluoro...)Show SMILES CC(=O)Nc1ccc(cc1OCCO)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C22H20F3N3O4S/c1-13(30)27-18-6-5-15(11-19(18)32-8-7-29)20(31)28-21-26-12-17(33-21)10-14-3-2-4-16(9-14)22(23,24)25/h2-6,9,11-12,29H,7-8,10H2,1H3,(H,27,30)(H,26,28,31) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of stearoyl-CoA desaturase 1 in human microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this
Ligand-Target Pair | |