Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM197464
(US9216968, 63 | US9732066, 63)Show SMILES CC(=O)OCc1nc2c(cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1)C(=O)Nc1cccc(Cl)c1C Show InChI InChI=1S/C26H20ClF3N4O4/c1-13-19(27)8-5-9-20(13)33-25(37)17-10-15(11-21-23(17)34-22(32-21)12-38-14(2)35)31-24(36)16-6-3-4-7-18(16)26(28,29)30/h3-11H,12H2,1-2H3,(H,31,36)(H,32,34)(H,33,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
NIPPON SHINY AKU CO., LTD.
US Patent
| Assay Description
mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu... |
US Patent US9732066 (2017)
BindingDB Entry DOI: 10.7270/Q2K35WSW |
More data for this
Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM197464
(US9216968, 63 | US9732066, 63)Show SMILES CC(=O)OCc1nc2c(cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1)C(=O)Nc1cccc(Cl)c1C Show InChI InChI=1S/C26H20ClF3N4O4/c1-13-19(27)8-5-9-20(13)33-25(37)17-10-15(11-21-23(17)34-22(32-21)12-38-14(2)35)31-24(36)16-6-3-4-7-18(16)26(28,29)30/h3-11H,12H2,1-2H3,(H,31,36)(H,32,34)(H,33,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
NIPPON SHINYAKU CO., LTD.
US Patent
| Assay Description
mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu... |
US Patent US9216968 (2015)
BindingDB Entry DOI: 10.7270/Q2KS6QCQ |
More data for this
Ligand-Target Pair | |