Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Receptor-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human)) | BDBM50528224
(CHEMBL4548552)Show SMILES CC(=O)c1cccc(NC(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3)ccc2F)c1 Show InChI InChI=1S/C26H21FN4O4S/c1-14(32)16-3-2-4-17(11-16)28-25(34)29-22-12-18(7-9-20(22)27)35-19-8-10-21-23(13-19)36-26(30-21)31-24(33)15-5-6-15/h2-4,7-13,15H,5-6H2,1H3,(H2,28,29,34)(H,30,31,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ningxia Medical University
Curated by ChEMBL
| Assay Description
Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system after 1 hr by quantitative PC... |
J Med Chem 62: 6665-6681 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00611
BindingDB Entry DOI: 10.7270/Q27D2ZMB |
More data for this
Ligand-Target Pair | |
Receptor-interacting serine/threonine-protein kinase 3
(Homo sapiens (Human)) | BDBM50528224
(CHEMBL4548552)Show SMILES CC(=O)c1cccc(NC(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3)ccc2F)c1 Show InChI InChI=1S/C26H21FN4O4S/c1-14(32)16-3-2-4-17(11-16)28-25(34)29-22-12-18(7-9-20(22)27)35-19-8-10-21-23(13-19)36-26(30-21)31-24(33)15-5-6-15/h2-4,7-13,15H,5-6H2,1H3,(H2,28,29,34)(H,30,31,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a |
Ningxia Medical University
Curated by ChEMBL
| Assay Description
Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system after 1 hr by quantitative PC... |
J Med Chem 62: 6665-6681 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00611
BindingDB Entry DOI: 10.7270/Q27D2ZMB |
More data for this
Ligand-Target Pair | |