Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1
(GUINEA PIG) | BDBM50084781
(2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-N-[4-...)Show SMILES CC(C(=O)NCc1ccc(cc1)-c1nnn[nH]1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 Show InChI InChI=1S/C31H26N6O2/c1-20(31(38)32-18-21-6-8-23(9-7-21)30-34-36-37-35-30)24-10-11-26-17-28(15-13-25(26)16-24)39-19-27-14-12-22-4-2-3-5-29(22)33-27/h2-17,20H,18-19H2,1H3,(H,32,38)(H,34,35,36,37) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 9.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratorios Menarini
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes |
J Med Chem 43: 392-400 (2000)
BindingDB Entry DOI: 10.7270/Q2DJ5DVX |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50084781
(2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-N-[4-...)Show SMILES CC(C(=O)NCc1ccc(cc1)-c1nnn[nH]1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 Show InChI InChI=1S/C31H26N6O2/c1-20(31(38)32-18-21-6-8-23(9-7-21)30-34-36-37-35-30)24-10-11-26-17-28(15-13-25(26)16-24)39-19-27-14-12-22-4-2-3-5-29(22)33-27/h2-17,20H,18-19H2,1H3,(H,32,38)(H,34,35,36,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L... |
Bioorg Med Chem 18: 5519-27 (2010)
Article DOI: 10.1016/j.bmc.2010.06.047
BindingDB Entry DOI: 10.7270/Q26D5TZ0 |
More data for this
Ligand-Target Pair | |