Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 490.5 BDBM50323894

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50323894 (2-(3-(2-(6-(quinolin-2-ylmethoxy)naphthalen-2-yl)p...) Show SMILES CC(C(=O)Nc1cccc(CC(O)=O)c1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 Show InChI InChI=1S/C31H26N2O4/c1-20(31(36)33-26-7-4-5-21(15-26)16-30(34)35)23-9-10-25-18-28(14-12-24(25)17-23)37-19-27-13-11-22-6-2-3-8-29(22)32-27/h2-15,17-18,20H,16,19H2,1H3,(H,33,36)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...				Bioorg Med Chem 18: 5519-27 (2010) Article DOI: 10.1016/j.bmc.2010.06.047 BindingDB Entry DOI: 10.7270/Q26D5TZ0
					More data for this Ligand-Target Pair