Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM302851
(7-(tert-Butyl)-2-(3-chloro-4-fluorophenyl)-N-(4-cy...)Show SMILES CC(C)(C)[C@@H]1CN(Cc2c(C(N)=O)c(nn12)-c1ccc(F)c(Cl)c1)C(=O)Nc1ccc(cc1)C#N |r| Show InChI InChI=1S/C25H24ClFN6O2/c1-25(2,3)20-13-32(24(35)30-16-7-4-14(11-28)5-8-16)12-19-21(23(29)34)22(31-33(19)20)15-6-9-18(27)17(26)10-15/h4-10,20H,12-13H2,1-3H3,(H2,29,34)(H,30,35)/t20-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst... |
US Patent US9598423 (2017)
BindingDB Entry DOI: 10.7270/Q2FJ2JT9 |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM302851
(7-(tert-Butyl)-2-(3-chloro-4-fluorophenyl)-N-(4-cy...)Show SMILES CC(C)(C)[C@@H]1CN(Cc2c(C(N)=O)c(nn12)-c1ccc(F)c(Cl)c1)C(=O)Nc1ccc(cc1)C#N |r| Show InChI InChI=1S/C25H24ClFN6O2/c1-25(2,3)20-13-32(24(35)30-16-7-4-14(11-28)5-8-16)12-19-21(23(29)34)22(31-33(19)20)15-6-9-18(27)17(26)10-15/h4-10,20H,12-13H2,1-3H3,(H2,29,34)(H,30,35)/t20-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst... |
US Patent US9598423 (2017)
BindingDB Entry DOI: 10.7270/Q2FJ2JT9 |
More data for this
Ligand-Target Pair | |