Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Calcitonin gene-related peptide type 1 receptor
(Homo sapiens (Human)) | BDBM50447344
(CHEMBL3114477)Show SMILES CC(C)(C)CCN1C(SC(CC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)C1=O)c1ccccc1N1CCC(O)CC1 Show InChI InChI=1S/C35H47N5O4S/c1-35(2,3)16-21-39-32(43)30(45-33(39)27-9-5-7-11-29(27)37-19-14-26(41)15-20-37)22-31(42)38-17-12-25(13-18-38)40-23-24-8-4-6-10-28(24)36-34(40)44/h4-11,25-26,30,33,41H,12-23H2,1-3H3,(H,36,44) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membranes preincubated for 30 mins followed by radioligand addition measured afte... |
Bioorg Med Chem Lett 24: 845-9 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.089
BindingDB Entry DOI: 10.7270/Q2FJ2J84 |
More data for this
Ligand-Target Pair | |
Calcitonin gene-related peptide type 1 receptor
(Homo sapiens (Human)) | BDBM50447344
(CHEMBL3114477)Show SMILES CC(C)(C)CCN1C(SC(CC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)C1=O)c1ccccc1N1CCC(O)CC1 Show InChI InChI=1S/C35H47N5O4S/c1-35(2,3)16-21-39-32(43)30(45-33(39)27-9-5-7-11-29(27)37-19-14-26(41)15-20-37)22-31(42)38-17-12-25(13-18-38)40-23-24-8-4-6-10-28(24)36-34(40)44/h4-11,25-26,30,33,41H,12-23H2,1-3H3,(H,36,44) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production preincubated for 30 mins follow... |
Bioorg Med Chem Lett 24: 845-9 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.089
BindingDB Entry DOI: 10.7270/Q2FJ2J84 |
More data for this
Ligand-Target Pair | |