Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286291
(5-amino-1-(tert-butyl)-3-(7- (neopentyloxy)quinoli...)Show SMILES CC(C)(C)COc1ccc2cc(cnc2c1)-c1nn(c(N)c1C(N)=O)C(C)(C)C Show InChI InChI=1S/C22H29N5O2/c1-21(2,3)12-29-15-8-7-13-9-14(11-25-16(13)10-15)18-17(20(24)28)19(23)27(26-18)22(4,5)6/h7-11H,12,23H2,1-6H3,(H2,24,28) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 175 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this
Ligand-Target Pair | |
Uncharacterized protein
(Cryptosporidium parvum) | BDBM286291
(5-amino-1-(tert-butyl)-3-(7- (neopentyloxy)quinoli...)Show SMILES CC(C)(C)COc1ccc2cc(cnc2c1)-c1nn(c(N)c1C(N)=O)C(C)(C)C Show InChI InChI=1S/C22H29N5O2/c1-21(2,3)12-29-15-8-7-13-9-14(11-25-16(13)10-15)18-17(20(24)28)19(23)27(26-18)22(4,5)6/h7-11H,12,23H2,1-6H3,(H2,24,28) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 255 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this
Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286291
(5-amino-1-(tert-butyl)-3-(7- (neopentyloxy)quinoli...)Show SMILES CC(C)(C)COc1ccc2cc(cnc2c1)-c1nn(c(N)c1C(N)=O)C(C)(C)C Show InChI InChI=1S/C22H29N5O2/c1-21(2,3)12-29-15-8-7-13-9-14(11-25-16(13)10-15)18-17(20(24)28)19(23)27(26-18)22(4,5)6/h7-11H,12,23H2,1-6H3,(H2,24,28) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 258 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this
Ligand-Target Pair | |
Calcium-dependent protein kinase 1
(Cryptosporidium parvum) | BDBM286291
(5-amino-1-(tert-butyl)-3-(7- (neopentyloxy)quinoli...)Show SMILES CC(C)(C)COc1ccc2cc(cnc2c1)-c1nn(c(N)c1C(N)=O)C(C)(C)C Show InChI InChI=1S/C22H29N5O2/c1-21(2,3)12-29-15-8-7-13-9-14(11-25-16(13)10-15)18-17(20(24)28)19(23)27(26-18)22(4,5)6/h7-11H,12,23H2,1-6H3,(H2,24,28) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this
Ligand-Target Pair | |